I already tried that. What I ended up doing was to forget trying to add the Uploader control programatically in C#. Everything I tried caused undefined indentifiers in JavaScript. I instead just add an iframe inside of the update panel and set up the control in a new *.aspx page as the "src" attribute. That was the only way I could get it to work.
All of the Uploader demos appear to be on static pages. Cutesoft needs to make a demo that adds the control progromatically to the page via the server in VB and C#.