the server global output for script name is:
$_SERVER['SCRIPT_NAME'] = /wp-admin/admin.php
the output url is:
http://domain.com/wp-admin/phpuploader/ajaxuploaderresource.php?type=script
Which is not correct. The correct path is doamin.com/wp-content/mu-plugins/phpuploader
I do have things working on my production server, but it is not a full proof solution, I will test any other methods you would like or I canlook at this more when I have resolved some other issues my host has caused with this migration/upgrade they have done to me hosting.
Thanks,
Jesse